Head back to Manny to start the mission. Take a car over to the marker and shoot the gang members on foot, then follow the car that takes off and do a driveby on it. Shoot any gang members that manage to flee from the car and your done.
You'll get a call from Mallorie opening up a new strand of missions for Elizabeta, but in the meantime head back to Brucie's apartment for the next mission.
Next: Out of the Closet: Part One
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